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The NFL betting panorama seems dramatically totally different just one-third into the season.
From a new Super Bowl favourite to a gorgeous injury-driven collapse and a shock chief in the Rookie of the Year race, oddsmakers have been busy adjusting their forecasts.
Here are 4 of the largest betting developments heading into Week 7.
49ers overtake Rams as Super Bowl favorites
The 49ers are the new staff to beat in the Super Bowl futures market.
San Francisco improved to 6-0 with Monday’s win over Washington, shifting from +680 to +540 at DraftKings Sportsbook.
Meanwhile, the Rams’ disastrous begin continues to take a toll on their championship hopes.
Los Angeles, which entered the season as the Super Bowl favourite, dropped to 2-4 after Sunday’s surprising loss to the Cardinals as 12.5-point favorites.
The Rams have plummeted from +700 to 12/1 in just one week.
Eagles’ odds collapse after Jalen Hurts damage
Philadelphia’s season has gone from dangerous to worse.
The Eagles have lost 4 straight video games, and the information that Jalen Hurts will miss the relaxation of the season due to blood clots has despatched their Super Bowl odds tumbling from 40/1 to 200/1 at DraftKings.
Philadelphia Eagles quarterback Jalen Hurts (1) drops back to cross during the second half against the Jacksonville Jaguars at Tottenham Hotspur Stadium in Tottenham, England, Sunday, Oct. 11, 2026. IMAGN IMAGES via Reuters Connect
The fallout has prolonged to the point-spread market.
Philadelphia opened as a 3-point favourite against Dallas on Monday night time but is now a 5.5-point dwelling underdog — a staggering 8.5-point swing.
Undefeated Chiefs are underdogs to struggling Seahawks
Kansas City has yet to lose a sport this season, but oddsmakers apparently aren’t satisfied.
Despite their 5-0 report, the Chiefs are 2.5-point underdogs against the defending champion Seahawks on Sunday night time.
Patrick Mahomes (15) of the Kansas City Chiefs scrambles during the second quarter against the Indianapolis Colts at Arrowhead Stadium in Kansas City, Mo., Sunday, Sept. 20, 2026. Getty Images
Seattle has dropped two straight video games and is just 1-3-2 against the unfold this season.
The Seahawks opened as 1.5-point favorites, but the line has moved another level in their favor.
It’s the first time Patrick Mahomes and Co. have been underdogs this season.
Carnell Tate takes over Offensive Rookie of the Year race
The Offensive Rookie of the Year market has a new favourite.
Titans extensive receiver Carnell Tate has surged to +200 at DraftKings, overtaking Denzel Boston, who led the pack just last week.
Betting on the NFL?
Tate caught six passes for 70 yards and his first NFL landing Sunday against the Colts, bringing his season totals to 29 receptions and 344 yards.
He was listed at +500 last week.
Jeremiyah Love (+300) and Boston (+400) stay his closest competitors in an more and more aggressive awards race.
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Dylan Svoboda is a versatile author and analyst across many sports activities. He’s notably educated about the huge three — MLB, the NFL and the NBA.